@article{SPINU_CEBOTARI_SAJIN_SPINU_DONOS_VOLNEANSCHI_GOSTEV_DOPIRA_2021, title={Assessment of anti SARS-CoV-2 antibodies present in convalescent plasma donors aimed at being used in COVID-19 treatment}, volume={2}, url={https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/124}, DOI={10.38045/ohrm.2021.2.08}, abstractNote={<p><strong><em>Introduction. </em></strong><em>Currently, COVID-19 treatment includes several options, including the use of convalescent plasma. Therefore, the presence of anti-SARS-CoV-2 in blood donors after the clinical recovery of COVID-19, depending on their place of residence, age and the clinical manifestation of the disease is of scientific-practical interest.</em></p> <p><strong><em>Material and methods.</em></strong><em> A total of 119 donors among patients were examined, namely males aged 18-60 years, having a past history of COVID-19 disease, being confirmed by PCR and treated, showing a negative PCR-based test result, which was performed at least 14 days after clinical recovery. The presence/absence of anti-SARS-CoV-2 was assessed by enzyme-linked immunosorbent assay.</em></p> <p><strong><em>Results.</em></strong><em> The obtained data showed that 87.4% of plasma donors responded to COVID-19 infection by anti-SARS-CoV-2 IgG expression, being predominantly found in the 26-35 age group. Most donors experienced mild and medium clinical forms. It is important to note that all severe clinical manifestations of the infection were followed by formation of anti-SARS-CoV-2 IgG. Urban living environment was predominantly found in convalescent donors (75.0%), which indicates that they are better informed by medical institutions.</em></p> <p><strong><em>Conclusions.</em></strong><em> The study shows that male blood donors aged 18-60 years, subsequently cured and being positive to anti-SARS-CoV-2 IgG can serve as a source of fresh plasma used for the treatment of COVID-19 patients.</em></p&gt;}, number={2}, journal={One Health & Risk Management }, author={SPINU, Constantin and CEBOTARI, Svetlana and SAJIN, Octavian and SPINU, Igor and DONOS, Ala and VOLNEANSCHI, Ana and GOSTEV, Igor and DOPIRA, Iurie}, year={2021}, month={Apr.}, pages={58-64} }